Humanity 2.0 starts to challenge a lot of the assumptions of Humanity 1.0, especially in terms of issues having to do with limitations. So in other words, you might say there are two ways to go on Humanity 2.0. And in my writing, I associate these with the transhuman and the posthuman, respectively.
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Of all the different issues we face, three problems pose existential challenges to our species. These three existential challenges are nuclear war, ecological collapse, and technological disruption. We should focus on them.